Hemeoxygenase expression in human placenta and placental bed implies a role in regulation of trophoblast invasion and placental function.

@article{Lyall2000HemeoxygenaseEI,
  title={Hemeoxygenase expression in human placenta and placental bed implies a role in regulation of trophoblast invasion and placental function.},
  author={Fiona Lyall and Annabel Barber and Leslie Myatt and Judith N. Bulmer and Stephen C. Robson},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2000},
  volume={14 1},
  pages={208-19}
}
The purpose of this study was to examine the expression of hemeoxygenases HO-1 and HO-2, which are responsible for the production of carbon monoxide (CO), in the human placenta and placental bed and to determine the role of inhibitors of HO on placental perfusion pressure. We hypothesized that HO is expressed within the placenta and that invading cytotrophoblast cells (CTB) express HO isoforms. The expression of HO-1 and HO-2 was studied on placenta and placental bed biopsies, obtained using a… CONTINUE READING