Heme oxygenase-1 polymorphism associated with severity of chronic obstructive pulmonary disease.

@article{Fu2007HemeOP,
  title={Heme oxygenase-1 polymorphism associated with severity of chronic obstructive pulmonary disease.},
  author={Wei-Ping Fu and Zhi-huan Zhao and Li-zhou Fang and Chang Sun and Lin Liu and Jian-Qin Zhang and Yaping Zhang and Lu-ming Dai},
  journal={Chinese medical journal},
  year={2007},
  volume={120 1},
  pages={12-6}
}
BACKGROUND Recent studies have suggested that susceptibility to chronic obstructive pulmonary disease (COPD) might be related to the length polymorphism of (GT)(n) repeat in the 5'-flanking region of heme oxygenase-1 (HOX-1) gene. However, there has been no research about the relationship between the polymorphism of HOX-1 gene and severity of COPD. METHODS The polymorphism of HOX-1 gene in 452 patients with COPD from Han population in Southwest China was analysed by fragment analysis. The… CONTINUE READING