Heme oxygenase-1-mediated host cell response inhibits the susceptibility of prostate cancer cells to retroviral infection and retards their proliferation.

@article{Zhou2013HemeOH,
  title={Heme oxygenase-1-mediated host cell response inhibits the susceptibility of prostate cancer cells to retroviral infection and retards their proliferation.},
  author={Zhao-Hua Zhou and Namita Kumari and Jennifer G Catalano and Sergei Nekhai and Jasen L. Wise and Kenneth M Yamada and Subhash Dhawan},
  journal={Current trends in immunology},
  year={2013},
  volume={14},
  pages={53-56}
}
Xenotropic murine leukemia virus-related virus (XMRV) resembles endogenous murine leukemia virus and was used in this study as a model for a new retrovirus infecting human cells. We demonstrate that induction of an HO-1-mediated host cell response inhibited the susceptibility of LNCaP prostate cancer cells to XMRV infection and efficiently retarded the… CONTINUE READING