Heme oxygenase-1 induction by hemin protects liver cells from ischemia/reperfusion injury in cirrhotic rats.

@article{Xue2007HemeOI,
  title={Heme oxygenase-1 induction by hemin protects liver cells from ischemia/reperfusion injury in cirrhotic rats.},
  author={Hui Xue and Hua Guo and Ying-chao Li and Zhi-ming Hao},
  journal={World journal of gastroenterology},
  year={2007},
  volume={13 40},
  pages={5384-90}
}
AIM To investigate the potential protective effect of HO-1 on cirrhotic liver cells in rats. METHODS Male Wistar rats included in the current study were randomly divided into 5 groups as follows: normal (N) group; liver cirrhotic (LC) group; sham (S) group; I/R group and I/R + hemin group. The model for inducing liver cirrhosis in rats was established according to a previously published protocol. Following this the segmental hepatic ischemia reperfusion operation was carried out. The rats… CONTINUE READING
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