Heme-oxygenase-1 implications in cell morphology and the adhesive behavior of prostate cancer cells

@inproceedings{Gueron2014Hemeoxygenase1II,
  title={Heme-oxygenase-1 implications in cell morphology and the adhesive behavior of prostate cancer cells},
  author={Geraldine Gueron and Jimena Giudice and Pia Valacco and Alejandra V Paez and Belen Elguero and Martin A Toscani and Felipe Mart{\'i}n Jaworski and Federico Coluccio Leskow and Javier Cotignola and Marcelo A. Marti and Mar{\'i}a A Binaghi and Nora Navone and Elba Susana Vazquez},
  booktitle={Oncotarget},
  year={2014}
}
Prostate cancer (PCa) is the second leading cause of cancer death in men. Although previous studies in PCa have focused on cell adherens junctions (AJs), key players in metastasis, they have left the molecular mechanisms unexplored. Inflammation and the involvement of reactive oxygen species (ROS) are critical in the regulation of cell adhesion and the integrity of the epithelium. Heme oxygenase-1 (HO-1) counteracts oxidative and inflammatory damage. Here, we investigated whether HO-1 is… CONTINUE READING
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Critical role of endogenous heme oxygenase 1 as a tuner of the invasive potential of prostate cancer cells

  • G Gueron, A De Siervi, +6 authors ES. Vazquez
  • Mol Cancer Res
  • 2009
Highly Influential
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