Heme oxygenase-1: a metabolic nike.

@article{Wegiel2014HemeOA,
  title={Heme oxygenase-1: a metabolic nike.},
  author={Barbara Wegiel and Zsuzsanna Nemeth and Matheus Correa-Costa and Andrew C Bulmer and Leo E Otterbein},
  journal={Antioxidants & redox signaling},
  year={2014},
  volume={20 11},
  pages={
          1709-22
        }
}
SIGNIFICANCE Heme degradation, which was described more than 30 years ago, is still very actively explored with many novel discoveries on its role in various disease models every year. RECENT ADVANCES The heme oxygenases (HO) are metabolic enzymes that utilize NADPH and oxygen to break apart the heme moiety liberating biliverdin (BV), carbon monoxide (CO), and iron. Heme that is derived from hemoproteins can be toxic to the cells and if not removed immediately, it causes cell apoptosis and… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 60 CITATIONS, ESTIMATED 52% COVERAGE

Redox Homeostasis and Cellular Antioxidant Systems: Crucial Players in Cancer Growth and Therapy

  • Oxidative medicine and cellular longevity
  • 2016
VIEW 15 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

PDGF-C and PDGF-D in ocular diseases.

  • Molecular aspects of medicine
  • 2017
VIEW 2 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Oxidative Stress and the Homeodynamics of Iron Metabolism

VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2014
2019

CITATION STATISTICS

  • 4 Highly Influenced Citations

  • Averaged 11 Citations per year from 2017 through 2019