Heme oxygenase: A novel target for the modulation of inflammatory response

@article{Willis1996HemeOA,
  title={Heme oxygenase: A novel target for the modulation of inflammatory response},
  author={Dean Adam Willis and Adrian Moore and R Miller Frederick and Derek Albert Willoughby},
  journal={Nature Medicine},
  year={1996},
  volume={2},
  pages={87-90}
}
Chronic inflammatory diseases place a heavy social and economic burden on the resources of many nations, but the number of safe and effective treatments is limited. To date, the major research effort has concentrated on those mediators responsible for the initiation and maintenance of the pathological process. In contrast, little attention has been focused on endogenous factors responsible for the resolution of the inflammation. Heme oxygenase ((HO); EC 1.14.99.3) is the rate–limiting enzyme in… CONTINUE READING
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