Heme overload inhibits the growth of normal rats.

Abstract

We have developed a model with which to evaluate the direct metabolic effect of circulating heme in chronic hemolytic diseases. Normal rats were injected with heme intraperitoneally (IP) using different treatment schedules and then killed so their growth parameters could be measured; heme injections were well tolerated, but final body weight was decreased… (More)

Topics

  • Presentations referencing similar topics