Heme binding by a bacterial repressor protein, the gene product of the ferric uptake regulation (fur) gene of Escherichia coli.

Abstract

The fur gene product, Fur, of Escherichia coli is a repressor when it binds Fe(II). Since heme and iron metabolism are closely linked and Fur is rich in histidine, a ligand for heme, the binding of heme to Fur was investigated. The oxidized Fur-heme complex is stable and low spin with a Soret maximum at 404 nm and no 620-nm band. CO coordinates with the… (More)

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@article{Smith1996HemeBB, title={Heme binding by a bacterial repressor protein, the gene product of the ferric uptake regulation (fur) gene of Escherichia coli.}, author={A. Smith and Neale Hooper and Natalia V Shipulina and W. T. Morgan}, journal={Journal of protein chemistry}, year={1996}, volume={15 6}, pages={575-83} }