Heme as a Target for Therapeutic Interventions

  title={Heme as a Target for Therapeutic Interventions},
  author={Stephan Immenschuh and Vijith Vijayan and Sabina M. Janciauskiene and Faikah Gueler},
  booktitle={Front. Pharmacol.},
Heme is a complex of iron and the tetrapyrrole protoporphyrin IX with essential functions in aerobic organisms. Heme is the prosthetic group of hemoproteins such as hemoglobin and myoglobin, which are crucial for reversible oxygen binding and transport. By contrast, high levels of free heme, which may occur in various pathophysiological conditions, are… CONTINUE READING