Hematoxylin and safranin O staining of frozen sections.

@article{Tran2000HematoxylinAS,
  title={Hematoxylin and safranin O staining of frozen sections.},
  author={Dinh Nam Tran and M Golick and Harold Rabinovitz and D Rivlin and George Elgart and B Nordlow},
  journal={Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]},
  year={2000},
  volume={26 3},
  pages={197-9}
}
Currently the hematoxylin and eosin staining procedure is the most popular among Mohs surgeons for histology. However, safranin O, a cheaper and relatively safer stain which is predominantly used for plant histology, should be considered as it offers similar or improved accuracy in the diagnosis of frozen sections of basal and squamous cell carcinomas.