Hematoxylin: Mesoamerica’s Gift to Histopathology. Palo de Campeche (Logwood Tree), Pirates’ Most Desired Treasure, and Irreplaceable Tissue Stain

@article{OrtizHidalgo2019HematoxylinMG,
  title={Hematoxylin: Mesoamerica’s Gift to Histopathology. Palo de Campeche (Logwood Tree), Pirates’ Most Desired Treasure, and Irreplaceable Tissue Stain},
  author={Carlos Ortiz-Hidalgo and Sergio Pi{\~n}a‐Oviedo},
  journal={International Journal of Surgical Pathology},
  year={2019},
  volume={27},
  pages={14 - 4}
}
Hematoxylin is a basic dye derived from the heartwood of Palo de Campeche (Haematoxylum campechianum), the logwood tree native to Mexico and Central America. Haematoxylum means “bloodwood” in reference to its dark-red heartwood and campechianum refers to its site of origin, the coastal city of Campeche on the Yucatan Peninsula, Mexico. Hematoxylin is colorless but it turns into the color dye hematein after oxidation (ripening). The dyeing property of logwood was well-known to the natives of the… 
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