Hematopoietically-Expressed Homeobox Gene Three Widely-Evaluated Polymorphisms and Risk for Diabetes: A Meta-Analysis

@inproceedings{Li2012HematopoieticallyExpressedHG,
  title={Hematopoietically-Expressed Homeobox Gene Three Widely-Evaluated Polymorphisms and Risk for Diabetes: A Meta-Analysis},
  author={Xiaobo Li and Yuqiong Li and Bei Zhou Song and Shujie Guo and Shaoli Chu and Nan Jia and Wenquan Niu},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND The hematopoietically-expressed homeobox (HHEX) gene is identified as a promising candidate for type 2 diabetes by genome-wide association studies, triggering plenty of subsequent replications; however, the results are conflicting. We therefore conducted a meta-analysis of three widely-evaluated polymorphisms in HHEX gene and diabetes risk. METHODOLOGY/PRINCIPAL FINDINGS A random-effects model was adopted irrespective of heterogeneity. Data and study quality were assessed in… CONTINUE READING