Hematopoietic stem-cell transplantation for sickle cell disease: current evidence and opinions.

@article{Shenoy2013HematopoieticST,
  title={Hematopoietic stem-cell transplantation for sickle cell disease: current evidence and opinions.},
  author={Shalini Shenoy},
  journal={Therapeutic advances in hematology},
  year={2013},
  volume={4 5},
  pages={335-44}
}
With rapidly expanding evidence of benefit reported by several groups, allogeneic hematopoietic stem-cell transplantation has become an acceptable treatment option for sickle cell disease. It is currently the only curative therapy available. Hematopoietic stem-cell transplantation was offered primarily as a therapeutic option for severe sickle cell disease in the context of myeloablative matched sibling donor transplants over the last two decades and helped to establish the benefits of… CONTINUE READING