Hematopoietic stem cell transplantation for familial hemophagocytic lymphohistiocytosis and Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in Japan.

@article{Ohga2010HematopoieticSC,
  title={Hematopoietic stem cell transplantation for familial hemophagocytic lymphohistiocytosis and Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in Japan.},
  author={Shouichi Ohga and Kazuko Kudo and Eiichi Ishii and Satoshi Honjo and Akira Morimoto and Yuko Osugi and Akihisa Sawada and Masami Inoue and Ken Tabuchi and Nobuhiro Suzuki and Yasushi Ishida and Shinsaku Imashuku and Shunichi Kato and Toshiro Hara},
  journal={Pediatric blood & cancer},
  year={2010},
  volume={54 2},
  pages={299-306}
}
BACKGROUND Post-transplant outcomes of hemophagocytic lymphohistiocytosis (HLH) patients were analyzed in Japan where Epstein-Barr virus (EBV)-associated severe forms are problematic. METHODS Fifty-seven patients (43 familial HLH [12 FHL2, 11 FHL3, 20 undefined], 14 EBV-HLH) who underwent stem cell transplantation (SCT) between 1995 and 2005 were enrolled based on the nationwide registration. RESULTS Fifty-seven patients underwent 61 SCTs, including 4 consecutive SCTs. SCTs were employed… CONTINUE READING

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