Hematopoietic microenvironment and the role of mesenchymal stromal cells in its organization

Abstract

Hematopoiesis occurs in a specific microenvironment formed by the stroma of hematopoietic organs characterized by variable cellular composition. The combined action of stromal elements controls the proliferation and differentiation of hematopoietic cells by means of direct cell-cell interactions and the production of humoral factors. The role of different… (More)
DOI: 10.1134/S207908641504009X

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