Hematopoietic growth factors secreted by seven human pleural mesothelioma cell lines: interleukin-6 production as a common feature.

@article{Schmitter1992HematopoieticGF,
  title={Hematopoietic growth factors secreted by seven human pleural mesothelioma cell lines: interleukin-6 production as a common feature.},
  author={Daniela Schmitter and Betsy G. Lauber and Barbara Fagg and Rolf Arno Stahel},
  journal={International journal of cancer},
  year={1992},
  volume={51 2},
  pages={
          296-301
        }
}
Seven mesothelioma cell lines, established from patients with pleural mesothelioma, exhibited substantial heterogeneity regarding in vitro morphology and growth characteristics. Media conditioned by these cell lines and by MeT5A normal mesothelial cells were examined for (i) colony formation on human bone-marrow cells, (ii) hematopoietic growth-factor content and (iii) mitogenic activity on mesothelioma cells. Colony-stimulating activity was produced only by the ZL34 cell line. Analysis of… CONTINUE READING
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