Hematopoietic growth factors in the treatment of acquired bone marrow failure states.

  title={Hematopoietic growth factors in the treatment of acquired bone marrow failure states.},
  author={Judith C. W. Marsh and Arnold Ganser and Michael Stadler},
  journal={Seminars in hematology},
  volume={44 3},
In severe aplastic anemia (SAA), the use of hematopoietic growth factors (HGFs) to support blood counts is of limited value, as predicted by in vitro studies and measurement of endogenous serum levels of hematopoietic growth factors (HGF), which are markedly elevated. Benefit is usually only seen in those with less severe disease who are unlikely to require HGFs in practice. HGFs administered alone play no role in the treatment of SAA. The main indication for using HGFs, most often granulocyte… CONTINUE READING


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