Hematopoietic defects in mice lacking the sialomucin CD34.

  title={Hematopoietic defects in mice lacking the sialomucin CD34.},
  author={Jie Cheng and Susanne Baumhueter and Grace Cacalano and Karen Carver-Moore and Harold Thibodeaux and Ranjeny Thomas and Hal E. Broxmeyer and Scott Cooper and Nigel Hague and Marilyn J Moore and L A Lasky},
  volume={87 2},
Although the pluripotent hematopoietic stem cell can only be definitively identified by its ability to reconstitute the various mature blood lineages, a diversity of cell surface antigens have also been specifically recognized on this subset of hematopoietic progenitors. One such stem cell-associated antigen is the sialomucin CD34, a highly O-glycosylated cell surface glycoprotein that has also been shown to be expressed on all vascular endothelial cells throughout murine embryogenesis as well… CONTINUE READING


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