Hematopoietic damage prior to PBSCT and its influence on hematopoietic recovery.

  title={Hematopoietic damage prior to PBSCT and its influence on hematopoietic recovery.},
  author={Mar{\'i}a Consuelo del Ca{\~n}izo and Natividad L{\'o}pez and Lourdes V{\'a}zquez and Ma Eugenia Fern{\'a}ndez and B Ana and Mar{\'i}a Dolores Caballero and M. L. Amigo and Maria Vitoria Mateos and Norma Guti{\'e}rrez and J F San Migue},
  volume={84 6},
BACKGROUND AND OBJECTIVE Patients with malignancies receive chemotherapy to induce tumor remission which could damage hematopoiesis and adversely influence hematopoietic reconstitution after transplantation. In the present study we used a long-term culture (LTBMC) system and clonogenic assays to evaluate the marrow damage in patients selected to receive peripheral blood stem cell transplantation (PBSCT). DESIGN AND METHODS Thirty-five patients - 20 with breast cancer (BC), 9 with non-Hodgkin… CONTINUE READING
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