Hematopoietic contribution to skeletal muscle regeneration by myelomonocytic precursors.

  title={Hematopoietic contribution to skeletal muscle regeneration by myelomonocytic precursors.},
  author={Regis Doyonnas and Mark A Labarge and Alessandra Sacco and Carol A. Charlton and Helen M. Blau},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={101 37},
Adult bone marrow-derived cells can participate in muscle regeneration after bone marrow transplantation. In recent studies a single hematopoietic stem cell (HSC) was shown to give rise to cells that not only reconstituted all of the lineages of the blood, but also contributed to mature muscle fibers. However, the relevant HSC derivative with this potential has not yet been definitively identified. Here we use fluorescence-activated cell sorter-based protocols to test distinct hematopoietic… CONTINUE READING
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