Hematopoietic Stem Cell Transplant in Older Patients with MDS and Co-existing Myelofibrosis

Abstract

Background: Myelodysplastic syndrome with co-existing bone marrow fibrosis is associated with a dismal prognosis with conventional therapy. Allogeneic hematopoietic stem cell transplant (HSCT) offers the sole treatment approach that offers curative potential. HSCT has been utilized in younger patients with this disorder however with the advent of reduced… (More)

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