Hematopoietic Development of ES Cells in Culture.

  title={Hematopoietic Development of ES Cells in Culture.},
  author={Gordon M. Keller and Saiphone Webb and Marion Kennedy},
  journal={Methods in molecular medicine},
Under appropriate culture conditions, ES cells will spontaneously differentiate and generate colonies known as embryoid bodies (EBs) that contain precursors of multiple lineages, including those of the hematopoietic system (1-7). Previous studies have demonstrated that the molecular events leading to hematopoietic commitment, as well as the kinetics of lineage development within the EBs, parallel that found in the normal mouse embryo (5). More recent studies (8-11) have supported these earlier… CONTINUE READING

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Hematopoietic Development of ES Cells

  • M. Kennedy, M. Firpo, K. Choi, C. Wall, S. Robertson, N Kabrun
  • Nature 386,
  • 1997

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