Hematological and bone marrow parameters in busulfan-treated rats: effects of silymarin extract

@article{Honarmand2015HematologicalAB,
  title={Hematological and bone marrow parameters in busulfan-treated rats: effects of silymarin extract},
  author={M. Honarmand and J. Sajedianfard and S. Nazifi},
  journal={Comparative Clinical Pathology},
  year={2015},
  volume={24},
  pages={1515-1520}
}
Busulfan is an alkylating agent that can be used in the treatment and control of chronic myeloblastic leukemia. Milk thistle seed extract of dried herb in 1 to 4 % silymarin is a powerful antioxidant flavonoid. In this study, busulfan and bone marrow suppression were used to assess whether the effect of silymarin can suppress cell death, or at least reduce it. Forty-two Wistar male rats were fed with a standard diet, divided into six groups of eight rats and treated as follows. Group 1—control… Expand

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