Hematogones: a review and update.

  title={Hematogones: a review and update.},
  author={Deborah W. Sevilla and Adriana Ioana Colovai and Foxwell N Emmons and Govind Bhagat and Bachir Alobeid},
  journal={Leukemia & lymphoma},
  volume={51 1},
Our knowledge regarding the nature and function of 'hematogones' has evolved considerably, since the initial description more than 70 years ago. Once considered the 'mystery cells' of the bone marrow, major advances in immunology and flow cytometry have enabled us to better characterize these cells and recognize them as physiologic precursors of B-cells. In this review, we describe the morphologic and phenotypic characteristics and clinical relevance of hematogones, and report recent advances… CONTINUE READING