Hematocrit was not validated as a surrogate end point for survival among epoetin-treated hemodialysis patients.

Abstract

OBJECTIVE To evaluate the use of hematocrit as a surrogate end point for survival among end-stage renal disease (ESRD) patients treated with epoetin. STUDY DESIGN AND SETTING Using United States Renal Data System (USRDS) data, we conducted an observational prospective study to analyze the relationships among epoetin dose, hematocrit, and survival for 31… (More)

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