Hematite (Fe(2)O(3)) enhances benzo[a]pyrene genotoxicity in endotracheally treated rat, as determined by Comet Assay.

@article{Garry2003HematiteE,
  title={Hematite (Fe(2)O(3)) enhances benzo[a]pyrene genotoxicity in endotracheally treated rat, as determined by Comet Assay.},
  author={S{\'e}bastien Garry and Fabrice Nesslany and ElMoukhtar Aliouat and Jean-Marie Haguenoer and Daniel Marzin},
  journal={Mutation research},
  year={2003},
  volume={538 1-2},
  pages={19-29}
}
Since epidemiological studies have firmly implied the co-exposition between iron oxides and polycyclic aromatic hydrocarbons (PAH) as potential etiological factor involved in the excess of mortality by lung cancer in miners, experimental studies have been performed to investigate the role of iron particles on benzo[a]pyrene (B[a]P)-induced lung pathogenesis. In the present study, the alkaline single-cell gel electrophoresis (SCGE; Comet Assay) was used to measure DNA single-strand breaks in… CONTINUE READING

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