Hemagglutinin-neuraminidase-independent fusion activity of simian virus 5 fusion (F) protein: difference in conformation between fusogenic and nonfusogenic F proteins on the cell surface.

Abstract

The fusion (F) protein of simian virus 5 (SV5) strain W3A is known to induce cell fusion in the absence of hemagglutinin-neuraminidase (HN) protein. In contrast, the F protein of SV5 strain WR induces cell fusion only when coexpressed with the HN protein, the same as do other paramyxovirus F proteins. When Leu-22 in the subunit F2 of the WR F protein is… (More)

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@article{Tsurudome2001Hemagglutininneuraminidaseindepe, title={Hemagglutinin-neuraminidase-independent fusion activity of simian virus 5 fusion (F) protein: difference in conformation between fusogenic and nonfusogenic F proteins on the cell surface.}, author={Masato Tsurudome and M. Ito and M. Nishio and Masashi Kawano and Hisako Komada and Y. Ito}, journal={Journal of virology}, year={2001}, volume={75 19}, pages={8999-9009} }