Hemagglutinin-33 of type A botulinum neurotoxin complex binds with synaptotagmin II.

@article{Zhou2005Hemagglutinin33OT,
  title={Hemagglutinin-33 of type A botulinum neurotoxin complex binds with synaptotagmin II.},
  author={Yu Zhou and Sean Foss and Paul Lindo and Hemanta K Sarkar and Bal Ram Singh},
  journal={The FEBS journal},
  year={2005},
  volume={272 11},
  pages={2717-26}
}
Botulinum neurotoxin type A (BoNT/A), the most toxic substance known to mankind, is produced by Clostridium botulinum type A as a complex with a group of neurotoxin-associated proteins (NAPs) through polycistronic expression of a clustered group of genes. NAPs are known to protect BoNT against adverse environmental conditions and proteolytic digestion. Hemagglutinin-33 (Hn-33) is a 33 kDa subcomponent of NAPs that is resistant to protease digestion, a feature likely to be involved in the… CONTINUE READING

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