Hemagglutinin 1-specific immunoglobulin G and Fab molecules mediate postattachment neutralization of influenza A virus by inhibition of an early fusion event.

@article{Edwards2001Hemagglutinin1I,
  title={Hemagglutinin 1-specific immunoglobulin G and Fab molecules mediate postattachment neutralization of influenza A virus by inhibition of an early fusion event.},
  author={Mark J. J. Edwards and Nigel J. Dimmock},
  journal={Journal of virology},
  year={2001},
  volume={75 21},
  pages={10208-18}
}
In standard neutralization (STAN), virus and antibody are reacted together before inoculation of target cells, and inhibition of almost any of the processes concerned in the early interaction of virus and cell, including inhibition of virus attachment to cell receptors, can be the cause of neutralization by a particular monoclonal antibody (MAb). To simplify the interpretation of antibody action, we carried out a study of postattachment neutralization (PAN), where virus is allowed to attach to… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

The Density Code for the Development of a Vaccine?

Journal of pharmaceutical sciences • 2016

Functions of Antibodies.

Microbiology spectrum • 2014
View 1 Excerpt

eview onoclonal antibodies for prophylactic and therapeutic use against viral

nfections eonard Botha, Ashley C. Banyardb, +3 authors Anthony R. Fooksb
2013
View 1 Excerpt

Similar Papers

Loading similar papers…