Helper cells active in the generation of cytotoxicity to a syngeneic tumor.

@article{Hancock1981HelperCA,
  title={Helper cells active in the generation of cytotoxicity to a syngeneic tumor.},
  author={Elizabeth J. Hancock and Douglas G. Kilburn and Julia G. Levy},
  journal={Journal of immunology},
  year={1981},
  volume={127 4},
  pages={1394-7}
}
We have examined a population of thymic lymphocytes that augment the generation in vitro of specific cytotoxic T cells against P815.X2, a syngeneic tumor in DBA/2 mice. These helper cells are evident in the thymus of DBA/2 mice 5 to 7 days after subcutaneous injection of live P815 cells. They are Thy-1 positive, resistant to gamma radiation, antigen specific, and appear to exert their influence most effectively when added at the beginning of the culture.