Helminths, allergic disorders and IgE‐mediated immune responses: Where do we stand?

@article{Erb2007HelminthsAD,
  title={Helminths, allergic disorders and IgE‐mediated immune responses: Where do we stand?},
  author={Klaus Joseph Erb},
  journal={European Journal of Immunology},
  year={2007},
  volume={37}
}
  • K. Erb
  • Published 2007
  • Biology, Medicine
  • European Journal of Immunology
Th2 responses induced by allergens or helminths share many common features. However, allergen‐specific IgE can almost always be detected in atopic patients, whereas helminth‐specific IgE is often not detectable and anaphylaxis often occurs in atopy but not helminth infections. This may be due to T regulatory responses induced by the helminths or the lack of helminth‐specific IgE. Alternatively non‐specific IgE induced by the helminths may protect from mast cell or basophil degranulation by… Expand
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