Helminth-derived products inhibit the development of allergic responses in mice.

  title={Helminth-derived products inhibit the development of allergic responses in mice.},
  author={Claudia Milena Trujillo-Vargas and Melanie Werner-Klein and Gisela Wohlleben and Tobias Polte and Gesine Hansen and Stefan Ehlers and Klaus Joseph Erb},
  journal={American journal of respiratory and critical care medicine},
  volume={175 4},
RATIONALE Epidemiological studies suggest that infections with helminths protect from the development of asthma. Supporting this view is our published finding that infection with Nippostrongylus brasiliensis decreased ovalbumin-induced Th2 responses in the lung of mice. OBJECTIVES To evaluate if N. brasiliensis excretory-secretory products also prevent the development of asthma. METHODS Mice were immunized with ovalbumin/alum intraperitoneally in the absence or presence of helminthic… CONTINUE READING
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