Helminth-derived immunomodulatory molecules.

  title={Helminth-derived immunomodulatory molecules.},
  author={Poom Adisakwattana and Sean P Saunders and Hendrik J. Nel and Padraic G Fallon},
  journal={Advances in experimental medicine and biology},
Infection of man with parasitic helminths leads to potent activation and modulation of the host immune response. This modulation of immunity by helminth infections may have bystander effects in altering, either suppressing or exacerbating, unrelated inflammatory processes. Various ongoing clinical trials are testing the therapeutic application of helminth infection of patients with inflammatory diseases, including inflammatory bowel disease and allergic disorders. Rather than the use of live… CONTINUE READING