Helix-packing motifs in membrane proteins.


The fold of a helical membrane protein is largely determined by interactions between membrane-imbedded helices. To elucidate recurring helix-helix interaction motifs, we dissected the crystallographic structures of membrane proteins into a library of interacting helical pairs. The pairs were clustered according to their three-dimensional similarity (rmsd… (More)


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@article{Walters2006HelixpackingMI, title={Helix-packing motifs in membrane proteins.}, author={Richard F. Walters and William F. DeGrado}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2006}, volume={103 37}, pages={13658-63} }