Helicobacter pylori virulence factors affecting gastric proton pump expression and acid secretion.

@article{Hammond2015HelicobacterPV,
  title={Helicobacter pylori virulence factors affecting gastric proton pump expression and acid secretion.},
  author={Charles E. Hammond and Craig Cano Beeson and Giovanni Dell ’ Ariccia Luc Laeven Gustavo Suarez and Richard M Peek and Steffen Backert and Adam J. Smolka},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2015},
  volume={309 3},
  pages={G193-201}
}
Acute Helicobacter pylori infection of gastric epithelial cells and human gastric biopsies represses H,K-ATPase α subunit (HKα) gene expression and inhibits acid secretion, causing transient hypochlorhydria and supporting gastric H. pylori colonization. Infection by H. pylori strains deficient in the cag pathogenicity island (cag PAI) genes cagL, cagE, or cagM, which do not transfer CagA into host cells or induce interleukin-8 secretion, does not inhibit HKα expression, nor does a cagA… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS
8 Citations
58 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 58 references

Helicobacter pylori-induced post-transcriptional regulation of H,K-ATPase alpha subunit gene by miRNA

  • YM Zhang, CE Hammond, +4 authors AJ. Smolka
  • Am J Physiol Gastrointest Liver Physiol 306: G606…
  • 2014
1 Excerpt

Similar Papers

Loading similar papers…