Helicobacter pylori-negative gastric cancer: characteristics and endoscopic findings.

  title={Helicobacter pylori-negative gastric cancer: characteristics and endoscopic findings.},
  author={Yorimasa Yamamoto and Junko Fujisaki and Masami Omae and Toshiaki Hirasawa and Masahiro Igarashi},
  journal={Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society},
  volume={27 5},
Helicobacter pylori (H. pylori) leads to chronic gastritis and eventually causes gastric cancer. The prevalence of H. pylori infection is gradually decreasing with improvement of living conditions and eradication therapy. However, some reports have described cases of H. pylori-negative gastric cancers (HpNGC), and the prevalence was 0.42-5.4% of all gastric cancers. Diagnostic criteria of HpNGC vary among the different reports; thus, they have not yet been definitively established. We recommend… CONTINUE READING
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