Helicobacter pylori duodenal colonization is a strong risk factor for the development of duodenal ulcer.

@article{Pietroiusti2005HelicobacterPD,
  title={Helicobacter pylori duodenal colonization is a strong risk factor for the development of duodenal ulcer.},
  author={Antonio Pietroiusti and Ida Luzzi and M Jose Martinez G{\'o}mez and Andrea Magrini and Antonio Bergamaschi and Antonio Forlini and Alberto Galante},
  journal={Alimentary pharmacology & therapeutics},
  year={2005},
  volume={21 7},
  pages={909-15}
}
AIM To test the hypothesis that duodenal colonization represents the final crucial step in the development of Helicobacter pylori related duodenal ulcer. METHODS Patients with non-ulcer dyspepsia who had gastric colonization by H. pylori were included in the study. At baseline endoscopy, we evaluated the prevalence of duodenal colonization (culture, urease testing and histology), and cytotoxin-associated gene A status (polymerase chain reaction). No patients received eradication during 1 year… CONTINUE READING

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