Helicobacter pylori cagA+ strains and dissociation of gastric epithelial cell proliferation from apoptosis.

@article{Peek1997HelicobacterPC,
  title={Helicobacter pylori cagA+ strains and dissociation of gastric epithelial cell proliferation from apoptosis.},
  author={Richard M Peek and Steven F. Moss and Kok-mun Tham and Guillermo I Perez-Perez and Su Xing Wang and Geraldine P. G. Miller and John Christopher Atherton and Peter R. Holt and Martin J. Blaser},
  journal={Journal of the National Cancer Institute},
  year={1997},
  volume={89 12},
  pages={863-8}
}
BACKGROUND Infection with Helicobacter pylori induces chronic gastritis in virtually all infected persons, and such gastritis has been associated with an increased risk of developing gastric cancer. This risk is further enhanced with cagA+ (positive for cytotoxin-associated gene A) H. pylori strains and may be a consequence of induced gastric cell proliferation and/or alteration in apoptosis (programmed cell death) in the gastric epithelium. PURPOSE To determine whether the H. pylori cagA… CONTINUE READING
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