Helicobacter pylori Eradication Modulates Aberrant CpG Island Hypermethylation in Gastric Carcinogenesis.


Background/Aims Helicobacter pylori infection induces aberrant DNA methylation in gastric mucosa. We evaluated the long-term effect of H. pylori eradication on promotor CpG island hypermethylation in gastric carcinogenesis. Methods H. pylori-positive patients with gastric adenoma or early gastric cancer who underwent endoscopic resection were enrolled… (More)
DOI: 10.4166/kjg.2016.68.5.253