Helicobacter pylori Down-Regulates the Receptors of Vascular Endothelial Growth Factor and Angiopoietin in Vascular Endothelial Cells: Implications in the Impairment of Gastric Ulcer Healing

Once a peptic ulcer has developed, angiogenesis plays a critical role in its healing by enhancing the microcirculation in the healing site. Previous reports have shown that Helicobacter pylori infection delays the healing of chronic gastric ulcers. To elucidate the mechanism of delayed ulcer healing caused by H. pylori, we investigated the angiogenic… CONTINUE READING