Helicobacter pylori, T cells and cytokines: the "dangerous liaisons".

@article{DElios2005HelicobacterPT,
  title={Helicobacter pylori, T cells and cytokines: the "dangerous liaisons".},
  author={Mario Milco D'Elios and Amedeo Amedei and Marisa Benagiano and Annalisa Azzurri and Gianfranco Del Prete},
  journal={FEMS immunology and medical microbiology},
  year={2005},
  volume={44 2},
  pages={
          113-9
        }
}
Helicobacter pylori infection is the major cause of gastroduodenal pathologies, but only a minority of infected patients develop chronic and life threatening diseases, as peptic ulcer, gastric cancer, B-cell lymphoma, or autoimmune gastritis. The type of host immune response against H. pylori is crucial for the outcome of the infection. A predominant H. pylori-specific Th1 response, characterized by high IFN-gamma, TNF-alpha, and IL-12 production associates with peptic ulcer, whereas combined… CONTINUE READING

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