Helical peptide arrays for lead identification and interaction site mapping.

Abstract

Libraries composed of linear and cyclic peptides cannot fully represent the higher order structures of most antigenic sites. To map the binding site of ligands or antibodies, a larger part of the three-dimensional space should be sampled. Because parallel synthesis of large arrays of peptides on hydrogels is restricted to relatively small peptides, a simple… (More)
DOI: 10.1016/j.ab.2011.06.002

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Cite this paper

@article{Langedijk2011HelicalPA, title={Helical peptide arrays for lead identification and interaction site mapping.}, author={Johannes P. M. Langedijk and Maria J. Zekveld and Mariska Ruiter and Davide Corti and Jaap Willem Back}, journal={Analytical biochemistry}, year={2011}, volume={417 1}, pages={149-55} }