Helical extension of the neuronal SNARE complex into the membrane

  title={Helical extension of the neuronal SNARE complex into the membrane},
  author={Alexander Stein and Gert Weber and Markus C Wahl and Reinhard Jahn},
Neurotransmission relies on synaptic vesicles fusing with the membrane of nerve cells to release their neurotransmitter content into the synaptic cleft, a process requiring the assembly of several members of the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) family. SNAREs represent an evolutionarily conserved protein family that mediates membrane fusion in the secretory and endocytic pathways of eukaryotic cells. On membrane contact, these proteins assemble in… CONTINUE READING
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