Heilung durch verschiedene zentralwirksame Pharmaka bei an autochtonen 3-Methylcholanthren-Tumoren operierten Ratten

@article{Metzler2004HeilungDV,
  title={Heilung durch verschiedene zentralwirksame Pharmaka bei an autochtonen 3-Methylcholanthren-Tumoren operierten Ratten},
  author={Alexandra von Metzler},
  journal={Zeitschrift f{\"u}r Krebsforschung und Klinische Onkologie},
  year={2004},
  volume={83},
  pages={195-203}
}
Drugs like picrotoxine, apomorphine, ephedrine and strychnine, affecting the central nervous system, cured rats after surgical removal of methylcholanthrene tumours. Picrotoxine was most effective, in the dosage of 0.6 mg/kg s. c., all rats were cured. The therapeutic range of picrotoxine was remarkably small. Variations of only ±0.1 mg/kg of the optimal dosage, caused a 50% reduction of survival rate. Stimulation of the immune system could be excluded as an influence on survival. All animals… CONTINUE READING