Height and bone mineral density in androgen insensitivity syndrome with mutations in the androgen receptor gene
@article{Danilovic2006HeightAB, title={Height and bone mineral density in androgen insensitivity syndrome with mutations in the androgen receptor gene}, author={D. L. S. Danilovic and P. H. S. Correa and E. M. F. Costa and K. F. S. Melo and B. Mendonça and I. J. P. Arnhold}, journal={Osteoporosis International}, year={2006}, volume={18}, pages={369-374} }
Introduction and hypothesisAndrogen insensitivity syndrome (AIS) constitutes a natural model to study effects of androgens and estrogens on growth and bone density. We evaluated height and bone density in patients with AIS with mutations in the androgen receptor (AR) gene.MethodsA retrospective analysis was conducted of eight subjects with complete AIS (CAIS) and four with partial AIS (PAIS) submitted to gonadectomy followed by estrogen replacement, and three with PAIS who did not undergo… CONTINUE READING
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