Hedonic reactivity to sucrose in rats: modification by pimozide.

  title={Hedonic reactivity to sucrose in rats: modification by pimozide.},
  author={C S Bailey and Sigmund Hsiao and James King},
  journal={Physiology & behavior},
  volume={38 4},
Reward summation functions (RSFs) are an important way to dissociate and quantify hedonic and motor effects of neuroleptics. Previously used only with brain stimulation reinforcement, we demonstrate they will also work using sucrose solution reinforcement. Eighteen male rats were trained to lever press on a CRF schedule for 0.01 ml sucrose solution reinforcers of varying concentration (0.025, 0.05, 0.1, 0.3, 0.5, 0.7, 0.9, 1.1, 1.7, 2.3 M). Making the lever harder to press caused an increase in… CONTINUE READING