Hedgehog signaling regulates imaginal cell differentiation in a basally branching holometabolous insect.


The evolution of imaginal cells, or stem cell-like cells, contributed to the spectacular diversification of holometabolous insects, which undergo complete metamorphosis. The proliferation and differentiation of these imaginal cells is under the control of juvenile hormone (JH), but which patterning genes respond to JH is currently unknown. Here, the role of… (More)
DOI: 10.1016/j.ydbio.2015.05.020


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