Hedgehog signaling is involved in development of the neocortex.

  title={Hedgehog signaling is involved in development of the neocortex.},
  author={Munekazu Komada and Hirotomo Saitsu and Masato Kinboshi and Takashi Miura and Kohei Shiota and Makoto Ishibashi},
  volume={135 16},
Sonic hedgehog (Shh) function is essential for patterning and cell fate specification, particularly in ventral regions of the central nervous system. It is also a crucial mitogen for cerebellar granule neuron precursors and is important in maintenance of the stem cell niche in the postnatal telencephalon. Although it has been reported that Shh is expressed in the developing dorsal telencephalon, functions of Shh in this region are unclear, and detailed characterization of Shh mRNA transcripts… CONTINUE READING


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The origin and specification of cortical interneurons

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