Hedgehog signal transduction: signal integration and cross talk in development and cancer.

@article{Riobo2006HedgehogST,
  title={Hedgehog signal transduction: signal integration and cross talk in development and cancer.},
  author={Natalia A. Riobo and Ke Lu and Charles P. Emerson},
  journal={Cell cycle},
  year={2006},
  volume={5 15},
  pages={1612-5}
}
Hedgehog (HH) signaling regulates a diversity of processes involved in developmental patterning, stem cell growth and maintenance, and cancer etiology. Despite its biological importance, the HH signal transduction pathway remains largely mysterious. Our past understanding of the HH pathway signaling components and mechanisms came from groundbreaking genetic and biochemical studies in the fruit fly Drosophila melanogaster. Some of these mechanisms are strikingly conserved in vertebrates… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

Similar Papers

Loading similar papers…